Bromelain

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Bromelain: An Overview

Bromelain is a crude extract from the fruit or stem of pineapple [Ananas comosus (Linn.) Merr.] plant. It consists of different closely related proteinases which are good antiinflammatory, antithrombotic and fibrinolytic agents. The active fractions have been characterized biochemically and found to be effective after oral administration. It has earned universal acceptability as a phytotherapeu...

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Thermal stability of free bromelain and bromelain-polyphenol complex in pineapple juice

Pineapple (Ananas comosus), Bromeliaceae family, is a fruit grows in tropical countries including Malaysia. This fruit has several pharmacological benefits due to the presence of high concentration of bromelain (cysteine proteases). Condition of elevated temperature will induce deformation of enzyme and result in loss of activity. Sulfhydryl groups in cysteine proteases are readily to be oxidiz...

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Fractionation and specificity studies on stem bromelain.

The presence, in the juice of pineapples, of a proteolytic enzyme or enzymes under the name of bromelin (2) has long been known, and some of the characteristics of this enzyme have been described (3-7). The ,juice of the stem of the pineapple plant was found by Heinicke and Gortner (8) to contain a similar enzyme. The acetone precipitate from the stem juice, which is called stem bromelain,’ is ...

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Efficacy of selected purification techniques for bromelain

Bromelain is one of the vegetal proteases found in pineapple plant. It has numerous applications in food and pharmaceuticals. This review discussed different bromelain purification techniques which will assist in determining the effect of processing conditions on the purification efficacy. There are four purification techniques to be discussed, namely; reverse micellar system, aqueous two phase...

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Use of bromelain for mild ulcerative colitis.

To the Editor Uleerative eolitis is a chronic condition characterized by inflammation of the mucosal layer of the colon. Despite multiple treatments, some patients continue to be symptomatic and seek alternative iherapy. We describe two patients who achieved clinical and endoseopic remission after initiation of bromelain supplementation. A 67-year-old woman with a history of ulcerativc proctiti...

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ژورنال

عنوان ژورنال: Journal of Literature Pharmacy Sciences

سال: 2018

ISSN: 2630-5569

DOI: 10.5336/pharmsci.2017-56115